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Classification: Medical Devices

Component: PDRN (sodium DNA)

Packing unit: 5vial x 3mL / 1pack

Recell PDRN Skinboosters

When Hyaluronic Acid Skinboosters injection became one of the hottest skin rejuvenation treatment in Asia nowdays, the Korean PDRN Mesotherapy also known as DNA injection, or PDRN regeneration injection is already became the hottest treatment in the Korean plastic surgery clinics.  

Recell PDRN Skinboosters

Mechanism of PDRN (Poly Deoxy Ribo Nucleotide) Action

PDRN stimulates and increases the metabolic activity of cells in the skin called fibroblasts so that to regenerate key components of the skin such as collagen, glycosaminoglycans and glycoproteins. PDRNactivates tired aged and damaged cells to act younger and get to work again.

It also acts mechanically as a scaffolding for cells and the extracellular matrix to grow - they have a 3-dimensional structure where fibroblasts can use to produce its regenerative effects.

Furthermore, it provides building blocks for DNA synthesis. Through salvage pathways, the Polynucleotides are broken down by the body's processes into purines and pyrimidines, then recycled into new DNA again.

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What is PDRN injection?

Polydeoxyribonucleotide (PDRN) contains deoxyribonucleotide polymers where 50 to 2000 base pairs are combined in a chain, is known to accelerate cell proliferation by activating A2 subtype purinergic receptor and salvage pathway. PDRN helps the regeneration of skin and tissue,  it could also be used for clinical treatment of diabetic foot ulcers.  Since it helps the skin regeneration, it could be use after laser treatment. PDRN was indicated for tissue repair and treatment of wound in skin graft in 2008 by KFDA. PDRN was first approved for clinical use in Italy as a tissue repair stimulating agent.

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PDRN anti-aging mesotherapy.png

HP Nucleo Vital is the PDRN dermal care product for professional use. As well, HP Nucleo Vital is optimized for various skin care and treatment processes, and furthermore the efficacy and safety were approved through clinical studies by dermatological experts. HP Nucleo Vital improves skin rejuvenation and elasticity of the skin through stimulating fibroblast and collagen substances by promoting the secretion of various cell growth factors such as FGF, EGF and IGF. It also keeps Hyaluronic Acid within' the skin dermis, keeping skin moisture all the time. 

How does PDRN work?

1. Selectively binds to cell adenosine (A2) receptors to secrete anti-inflammatory cytokines (signals) and growth factors.

2. Fast tissue regeneration with less energy through the salvage pathway that reuses intermediates in DNA synthesis.

Regeneration of Extracellular matrix, it makes the skin healthy and elastic through the organization book circle. improves the environment in the skin and increases skin elasticity. Reconstructs damaged skin microenvironment , produces collagen to normalize cell tissue.

Tissue regeneration and anti-inflammatory substance

Fast and excellent effect 

Continuous regeneration effect

Exceptional safety and reliability

Low molecular weight

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