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Conjuran ®

Item name: Biomaterial for tissue restoration

Ingredients: Sodium Polynucleotide 20mg/mL

Purpose of use: It is used to reduce mechanical friction in the joint area through physical restoration by injecting it into the joint cavity.

Target patients: Radiologically low-grade (KL grade I, II, III) osteoarthritis of the knee joint

Administration period · Frequency:  up to 5 administrations within 6 months  * Same as sodium hyaluronate drug formulation · Simultaneous administration prohibited

Weight or packaging unit: 2mL X 1syringe / Box 

Storage method: room temperature (1~30°C)


What conjugate  Features points


Injection material for PN joint cavity

PN (polynucleotide, polynucleotide), a long chain DNA component extracted from salmonid fish, is a high-molecular tissue repair biomaterial that can be used in the joint cavity. It maintains a constant shape in the joint cavity  and is slowly decomposed.


Effects of Conjuran®

As a result of clinical trials, the use of Conjuran® three times reduced the VAS* level of the knee joint.

*VAS Abbreviation for "visual analog scale", which refers to a visual analog scale. It is one of the pain scales as a method to evaluate the intensity of subjective pain, and records 'no pain' on the left side of the line and 'unbearable pain' on the right side of the line, and the patient indicates the pain level.


Reduce knee joint friction

Conjuran® has high elasticity in the joint cavity to reduce cartilage friction.


low adverse reactions

Conjuran®'s main ingredient, PN, is used in joint cavities. 

It is a possible tissue repair biomaterial.

Concuran is a biomaterial for tissue repair that maintains a certain shape in the knee joint cavity, with PN (Polynucleotide), a DNA fraction extracted from salmon and fish, as its main component.

Sodium polynucleotide has the property of binding to a large amount of water molecules, so when combined with water molecules, it takes the form of a gel that exhibits high viscosity and elasticity, and is injected into the damaged joint to act as a buffer and lubricant.

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